Pathology of Bell's palsy.

J. Sadé
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引用次数: 25

Abstract

Segmental herniation of the facial nerve after epineural incision is regarded as proof that idiopathic Bell's palsy is due to elevated pressure caused by anoxia secondary to local vasospasm. However, epineural biopsies—taken at decompressions—have failed to reveal edema or other lesions. The nerve itself was observed to bulge through its entire intratympanic course. Idiopathic Bell's palsy often shows epidemiologic features and sometimes follows viral infections. Diabetes, especially latent diabetes, and arteriosclerosis are often associated with Bell's palsy—and could account for hemorrhages reported at the geniculate ganglion region. Bell's palsy is probably not one pathological entity—among its plausible causes are viral infections and vascular assaults both above the tympanic part of the facial nerve. The classical entrapment theory still awaits confirmation especially as myelin bulging is a normal phenomenon which becomes more pronounced in reaction to various injuries which are not necessarily local intratympanic ones.
贝尔氏麻痹的病理。
神经外切口后面神经节段性突出被认为是特发性贝尔麻痹是局部血管痉挛继发缺氧引起的血压升高的证据。然而,减压时进行的神经外活检未能发现水肿或其他病变。观察到神经本身在整个鼓室内突起。特发性贝尔氏麻痹常表现出流行病学特征,有时伴随病毒感染。糖尿病,尤其是潜伏性糖尿病和动脉硬化常与贝尔氏麻痹有关,这可能是膝状神经节区出血的原因。贝尔氏麻痹可能不是一种病理实体——其可能的原因是病毒感染和血管攻击,都在面神经的鼓室部分以上。经典的包裹理论仍有待证实,特别是髓鞘膨胀是一种正常现象,在各种损伤的反应中变得更加明显,而这些损伤不一定是局部的鼓室内损伤。
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