Maternal Seroprevalence of Hepatitis B Virus Serologic Markers among Attendees of a Secondary Health Facility in Maiduguri, Nigeria

British microbiology research journal Pub Date : 2016-01-10 DOI:10.9734/bmrj/2016/18201

S. Oyinloye, M. Osunkwo, B. Taki-Mohd, B. Ajayi, M. Lawan

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引用次数: 1

Abstract

The profile of four hepatitis B virus markers [Hepatitis B surface antigen (HBsAg), antibodies of the immunoglobulin M (IgM) class against the hepatitis B core antigen (IgM anti-HBc), Hepatitis B surface antibody (Anti-HBs) and Hepatitis B envelop antigen (HBeAg)] among pregnant women (n=91), with mean age of 25.96 years, were determined using Enzyme linked immunosorbent assay kit. A significant (p=0.00001) overall sero-prevalence of 8.79%, 36.26%, 6.59% and 7.65% were observed for HBsAg, Anti-HBs, IgM anti-HBc and HBeAg respectively. Forty seven point three percent were susceptible (HBsAg , IgM anti-HBc -ve and anti-HBs) to hepatitis B virus infection. One of thirteen pregnant women tested positive for HBsAg and HBeAg; this portends high risk of transmission to the fetus. This result portrays the unreliability of using presence of HBsAg as the Short Research Article Oyinloye et al.; BMRJ, 11(3): 1-7, 2016; Article no.BMRJ.18201 2 sole marker for hepatitis B virus infection, high susceptibility to hepatitis B virus infection and the risk of transmission of HBV to fetuses.

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尼日利亚迈杜古里一家二级卫生机构参与者中乙型肝炎病毒血清学标志物的母亲血清阳性率

采用酶联免疫吸附测定试剂盒对91例平均年龄25.96岁的孕妇进行4种乙肝病毒标志物[乙型肝炎表面抗原(HBsAg)、抗乙型肝炎核心抗原(IgM - hbc)、抗乙型肝炎表面抗体(Anti-HBs)和乙型肝炎包膜抗原(HBeAg)]的检测。HBsAg、Anti-HBs、IgM、anti-HBc和HBeAg的总体血清患病率分别为8.79%、36.26%、6.59%和7.65%，差异有统计学意义(p=0.00001)。47.3%的人对乙型肝炎病毒感染敏感(HBsAg, IgM - anti-HBc -ve和anti-HBs)。13名孕妇中有1名HBsAg和HBeAg检测呈阳性;这预示着传染给胎儿的风险很高。这一结果说明了使用HBsAg存在作为短研究文章的不可靠性。中国生物医学工程学报，2016,31 (3):1-7;文章no.BMRJ。18201乙型肝炎病毒感染的唯一标志物，乙型肝炎病毒感染的高易感性和乙型肝炎病毒传播给胎儿的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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British microbiology research journal

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