Antimicrobial activities of sweet orange (Citrus sinensis) juice on isolated Staphylococcus aureus, Escherichia coli, Pseudomonas spp, and Klebsiella spp

International Journal of Clinical Biochemistry and Research Pub Date : 2022-09-15 DOI:10.18231/j.ijcbr.2022.047

E. C. Ogbodo, J. Iwuji, S. Chukwuemeka, E. Ogbonye, A. Amah, I. Uduchi, A. Okezie, A. A. Okebalama

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Abstract

Resistance to antibiotics is one of the greatest problems to the success of modern medication. Due to the emergence of multi-drug resistant bacteria, selection of effective antibiotics for suppression of microbial activity has been an incidental issue. The aim of this study is to determine the antimicrobial activities of sweet orange juice on isolated, , which were subjected to different concentrations of sweet orange juice to determine their response to the juice concentrations. 25%, 50%, & 100% concentrations were used respectively using a well-in-agar diffusion method and it was discovered that all the microorganisms were sensitive to the sweet orange juice at 100% concentration only with zones of inhibitions as follows: This shows that the juice may not be recommended as alternative for antibiotics development since it only inhibited the microbial growth at 100% concentration only, and its respective zones of inhibition were minimal or less effective.

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甜橙汁对分离的金黄色葡萄球菌、大肠杆菌、假单胞菌和克雷伯氏菌的抑菌活性

对抗生素的耐药性是现代药物成功的最大问题之一。由于多重耐药细菌的出现，选择有效的抗生素来抑制微生物活性已经成为一个偶然的问题。本研究的目的是测定不同浓度的甜橙汁对分离体的抑菌活性，并测定其对不同浓度甜橙汁的反应。使用琼脂扩散法分别使用25%，50%和100%浓度，发现所有微生物对100%浓度的甜橙汁敏感，并且抑制区域如下:这表明果汁可能不推荐作为抗生素开发的替代品，因为它仅抑制100%浓度的微生物生长，其各自的抑制区域很小或效果较差。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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International Journal of Clinical Biochemistry and Research

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