Intraoperative awareness with recall during General Anaesthesia in Damascus University Hospitals in Syria

Najwa Rekmani, Deemah Soliman, Lamees Mansour, Zakaria Shahoud, Mhd Hosam Barazi
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Abstract

Background: Awareness with recall during general anesthesia is one of the frightening complications of general anesthesia, which indicates the failure of anesthesia. Awareness is an underestimated complication despite the fact that it sometimes carries devastating psychological risks for patients. To our knowledge this is the first research in Syria that reports the incidence of awareness with recall during general anesthesia. Aims: to assess the incidence of awareness with recall during general anesthesia in Damascus University teaching hospitals. Design: Multi-central prospective cohort study. Setting: Three main Teaching Hospitals of Damascus University: Al-Assad, Al-Mowassat & Maternity Hospitals during the time period between January and November 2021. Study Sample: 3500 patients aged ≥ 18 years were included. Results: the incidence of Awareness with recall during general anesthesia in Damascus University Teaching Hospitals was 0.66% in low risk of awareness surgery and 1.8% in high risk of awareness surgeries. The most frequent manifestations of awareness were auditory perceptions, paralysis and pain (100%, 100% & 97.4% respectively). Conclusions: Awareness with recall rate was somehow high in Damascus University Teaching Hospitals in comparison to the figures reported by American and European studies, this difference was especially noted in a low risk of awareness surgery. The rates were similar in the high risk of awareness surgeries. Lack of premedication and low concentration of inhalational agent were the main reasons for awareness.
叙利亚大马士革大学医院全麻期间术中意识与回忆
背景:全麻过程中伴有回忆的意识是全麻最可怕的并发症之一,预示着麻醉的失败。意识是一种被低估的并发症,尽管它有时会给患者带来毁灭性的心理风险。据我们所知,这是叙利亚第一个报告全身麻醉期间意识与回忆发生率的研究。目的:了解大马士革大学附属医院全麻患者意识与回忆的发生率。设计:多中心前瞻性队列研究。设置:2021年1月至11月期间,大马士革大学的三家主要教学医院:Al-Assad、Al-Mowassat和妇产医院。研究样本:纳入年龄≥18岁的患者3500例。结果:大马士革大学附属医院全麻中意识手术低风险患者的意识伴回忆发生率为0.66%,意识手术高风险患者的意识伴回忆发生率为1.8%。最常见的意识表现为听觉感知、麻痹和疼痛(分别为100%、100%和97.4%)。结论:与美国和欧洲研究报告的数据相比,大马士革大学教学医院的意识和回忆率在某种程度上较高,这种差异在低风险的意识手术中尤其明显。在高风险的意识手术中,这一比例相似。用药前缺乏和吸入剂浓度低是意识不清的主要原因。
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