Diffuse Astrocytoma and Ollier’s Disease

A. S. A. Rumeh, T. Shaikh, A. Lari, Abdullah Muharib, W. Shakweer
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Abstract

Several syndromes are associated with an increased incidence of intracranial tumors. Among these is enchondromatosis. It is a rare, nonhereditary condition. The common subtypes of enchondromatosis are Ollier’s disease (OD) and Maffucci syndrome. It has been distinguished between them by the presence of vascular malformation and non-skeletal neoplasm in Maffucci syndrome. The emergence of malignant neoplasms, including gliomas is a well-recognized complication in Maffucci syndrome, but over the past few years there has been an increasing number of reported cases of patients with intracranial tumors and OD. In our case report we discuss a 23-year-old female recently diagnosed with World Health Organization (WHO) grade II diffuse astrocytoma and found to have OD. J Neurol Res. 2020;10(6):240-244 doi: https://doi.org/10.14740/jnr580
弥漫性星形细胞瘤与奥利氏病
一些综合征与颅内肿瘤发生率增高有关。软骨瘤病就是其中之一。这是一种罕见的非遗传性疾病。内生性软骨瘤病的常见亚型有奥利氏病(Ollier’s disease, OD)和Maffucci综合征。它已经区分他们的存在血管畸形和非骨骼肿瘤的马夫奇综合征。恶性肿瘤的出现,包括胶质瘤,是Maffucci综合征的一个公认的并发症,但在过去的几年里,有越来越多的患者报告颅内肿瘤和OD的病例。在我们的病例报告中,我们讨论了一位23岁的女性,最近被诊断为世界卫生组织(WHO) II级弥漫性星形细胞瘤,并发现有过量。中华神经科学杂志,2020;10(6):240-244 doi: https://doi.org/10.14740/jnr580
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