Studies on the essential oil composition and antimicrobial activity of Thymus algeriensis Boiss. et Reut

International Journal of Aromatherapy Pub Date : 2006-01-01 DOI:10.1016/j.ijat.2006.04.003

T. Dob , D. Dahmane , T. Benabdelkader , C. Chelghoum

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引用次数: 96

Abstract

Many species of Thymus have been widely used in Algerian folk medicine as astringent, expectorant and cicatrising agents. This study was designed to investigate for the first time the essential oil of the aerial parts of wild growing Thymus algeriensis endemic in North Africa. The volatile oil obtained by hydrodistillation was characterized by the physico-chemical properties, GC and GC/MS techniques. The yield of the oil was 1.13% (w/w), based on dry weight. Fifty-five components, representing 94.3% of the total oil, were identified. The oil was distinguished by its high content of oxygenated monoterpenes (79.5%) and was found to possess the following major components: linalool (47.3%), thymol (29.2%) and p-cymene (6.8%). Furthermore, the oil was tested for antimicrobial activity against four bacteria, two fungi and two yeasts. This oil exhibited a significant in vitro antimicrobial activity against Bacillus subtilis (MIC = 0.5 μL/mL), as well as against all yeast and all filamentous fungi tested (MIC = 0.5 and 1.0 μL/mL).

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阿尔及利亚胸腺精油成分及抑菌活性研究。et Reut

许多种类的胸腺草在阿尔及利亚民间医学中被广泛用作收敛、祛痰和愈合剂。本研究首次对北非特有野生阿尔及利亚胸腺(thyymus algeriensis)地上部分的挥发油进行了研究。采用气相色谱(GC)和质谱(GC/MS)技术对加氢蒸馏得到的挥发油进行了理化性质表征。以干重为基准，油得率为1.13% (w/w)。鉴定出55种组分，占总油的94.3%。其主要成分为芳樟醇(47.3%)、百里香酚(29.2%)和对伞花烃(6.8%)。此外，还测试了该油对四种细菌、两种真菌和两种酵母的抗菌活性。该精油对枯草芽孢杆菌(MIC = 0.5 μL/mL)、酵母菌和丝状真菌(MIC = 0.5和1.0 μL/mL)均有显著的抑菌活性。

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International Journal of Aromatherapy

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