Epidermal growth factor receptor mutated lung cancer presenting as synchronous with a recurrent nonhuman papillomavirus-related head-and-neck squamous cell carcinoma
D. Fonseca, S. Arya, Vaishnavi Kunteepuram, K. N. N. Raju, S. Rajappa
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引用次数: 0
Abstract
A patient with nonhuman papillomavirus (HPV)-related head-and-neck cancers is at an increased risk of developing second primary malignancies. We present a case of non-HPV-related squamous cell carcinoma (SCC) of the left lower alveolus who presented with locoregional recurrence in the left upper lip 3 years after initial treatment with chemoradiotherapy along with a synchronous Epidermal growth factor receptor(EGFR)mutated lung adenocarcinoma. Comprehensive genomic profiling will guide diagnosis and therapy in these cases. Registry of synchronous tumors would help design protocols for better management.