Synthesis of linezolid

Meng Qing
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引用次数: 0

Abstract

Linezolid is synthetic oxazolidinone antibacterial agent against multidrug resistant strains that mainly inhibits gram positive bacteria.It inhibits synthesis of bacteria protein in early stage,on the contrary,other antibiotics inhibit in last stage.Three reactions of the method reported by literature have been modified and Linezolid has been successfully synthesized.
利奈唑胺的合成
利奈唑胺是一种合成的恶唑烷酮类抗菌剂,主要用于抑制革兰氏阳性菌的多重耐药菌株。对细菌蛋白的合成有早期抑制作用,对细菌蛋白的合成有后期抑制作用。对文献报道的三个反应进行了改进,成功合成了利奈唑胺。
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