Catastrophic antiphospholipid syndrome in a patient with immune thrombocytopenic purpura

IF 0.3 4区医学 Q4 ONCOLOGY

Uhod-Uluslararasi Hematoloji-Onkoloji Dergisi Pub Date : 2011-09-01 DOI:10.4999/UHOD.10095

S. John, K. McCrae

引用次数: 0

Abstract

A 47-year old Caucasian male with 7-year history of Immune Thrombocytopenic Purpura (ITP) presented with acute onset pain and purplish-blue discoloration of the left fifth toe and pleuritic chest pain. At the time of ITP diagnosis, he was positive for lupus anticoagulant (LA) and high titer of IgG anticardiolipin antibodies (aCL). However, his platelet count had previously remained stable at approximately 40,000/μL and he never required treatment. His examination was normal except for dusky cyanosis and coolness of the left fifth toe associated with extreme tenderness. Abnormal laboratory studies on admission included leukocytosis (11.610/μL), thrombocytopenia (76,000 /μL) and elevated D-dimer (770 ng/mL FEU). Cardiac enzymes, EKG and Chest X-ray were normal. A lower extremity arterial study done prior to admission was normal.

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免疫性血小板减少性紫癜患者的灾难性抗磷脂综合征

47岁白人男性，免疫性血小板减少性紫癜(ITP)病史7年，表现为急性疼痛，左第5趾紫蓝色变色，胸膜炎性胸痛。在ITP诊断时，他的狼疮抗凝血(LA)和高滴度的抗心磷脂抗体(aCL) IgG阳性。然而，他的血小板计数之前一直稳定在大约40,000/μL，他从未需要治疗。他的检查是正常的，除了暗绀和冷的左第五趾，并伴有极度压痛。入院时实验室检查异常包括白细胞增多(11.610/μL)、血小板减少(76000 /μL)和d -二聚体升高(770 ng/mL FEU)。心脏酶、心电图和胸片检查正常。入院前的下肢动脉检查是正常的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Uhod-Uluslararasi Hematoloji-Onkoloji Dergisi ONCOLOGY-

CiteScore

1.60

自引率

16.70%

发文量

审稿时长

>12 weeks

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