S. Esnault, J. Leet, M. Johansson, Karina T. Barretto, P. Fichtinger, F. J. Fogerty, K. Bernau, S. Mathur, D. Mosher, N. Sandbo, N. Jarjour
{"title":"Eosinophil cytolysis on Immunoglobulin G is associated with microtubule formation and suppression of rho‐associated protein kinase signalling","authors":"S. Esnault, J. Leet, M. Johansson, Karina T. Barretto, P. Fichtinger, F. J. Fogerty, K. Bernau, S. Mathur, D. Mosher, N. Sandbo, N. Jarjour","doi":"10.1111/cea.13538","DOIUrl":null,"url":null,"abstract":"The presence of eosinophils in the airway is associated with asthma severity and risk of exacerbations. Cell‐free eosinophil granules are found in tissues in eosinophilic diseases, including asthma. This suggests that eosinophils have lysed and released cellular content, likely harming tissues.","PeriodicalId":10148,"journal":{"name":"Clinical & Experimental Allergy","volume":"13 1","pages":"198 - 212"},"PeriodicalIF":0.0000,"publicationDate":"2019-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical & Experimental Allergy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/cea.13538","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 11
Abstract
The presence of eosinophils in the airway is associated with asthma severity and risk of exacerbations. Cell‐free eosinophil granules are found in tissues in eosinophilic diseases, including asthma. This suggests that eosinophils have lysed and released cellular content, likely harming tissues.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
