Evaluation of Medication Errors in Teaching Hospitals

F. Mousavi, S. Razavi, P. Shojaei
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Abstract

Introduction: Medication errors (MEs) are a common explanation for iatrogenic adverse events. This study appraised the incidence of MEs and identified the error types in the hospitals affiliated to Azad University of Medical Sciences, located in Tehran, Iran. Materials and Methods: This cross-sectional descriptive study was conducted on all patients admitted to the hospitals affiliated to Azad University of Medical Sciences. The data were collected by means of a drug safety checklist and then extracted and analyzed in SPSS software (version 22.0). Moreover, drug interaction was assessed based on the World Health Organization guidelines and Medscape application. Results: The mean MEs incidence was obtained as 43.38±5.25. Moreover, the mean numbers of errors in prescribing drugs and antibiotics were 4.71±2.93 and 1.02±0.95, respectively. According to the results, drug interactions occurred in 12.3% of the medicines. In addition, ME showed a significant correlation with education status, ward type, admission type, hepatic failure, hepatic enzymes, patient weight (when on antibiotics), antibiotic effect, and patient age (65> years). Conclusion: The results were indicative of a high prevalence of prescription errors. Moreover, it was found that most of MEs were made by doctors, mainly due to the lack of an electronic drug registration system. Therefore, physicians need to be educated on how to increase patient safety through drug safety.
教学医院用药差错评价
药物错误(MEs)是医源性不良事件的常见解释。本研究评估了位于伊朗德黑兰的阿扎德医学大学附属医院的MEs发生率,并确定了错误类型。材料和方法:本横断面描述性研究对所有在阿扎德医科大学附属医院住院的患者进行。采用药品安全检查表收集数据,用SPSS软件(22.0版)进行数据提取和分析。此外,根据世界卫生组织指南和Medscape应用评估药物相互作用。结果:MEs的平均发生率为43.38±5.25。处方错误次数平均为4.71±2.93次,抗生素处方错误次数平均为1.02±0.95次。结果显示,12.3%的药物发生相互作用。此外,ME与受教育程度、病房类型、住院类型、肝功能衰竭、肝酶、患者体重(使用抗生素时)、抗生素效果、患者年龄(65 ~ 60岁)有显著相关。结论:结果表明处方错误发生率较高。此外,调查发现,大多数微信是由医生开具的,主要原因是缺乏电子药品注册系统。因此,需要教育医生如何通过药物安全来提高患者的安全。
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