Colonic Slow Transit in Patients with Dyssynergic Defecation and Effectiveness of Biofeedback Therapy

D. Arı, Ömer Öztürk, Yasemin Özderi̇n, Dilara Turan Gökçe, İ. Tenlik, F. Bacaksız, V. Gökbulut, O. Coşkun
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Abstract

Background: Colonic transit is delayed in two-thirds of patients with dyssynergic defecation. As a result, it's possible that dyssynergic defecation and slow transit constipation are linked. There is a scarcity of research on the coexistence of dyssynergic defecation and slow transit constipation, as well as the efficacy of biofeedback therapy in this group of patients. Methods: The results of anorectal manometry and MR defecography were used to make the diagnosis of dyssynergic defecation. The colon transit time was measured with the help of 24 specially marked markers. All of the patients were given biofeedback therapy. Results: The average age of the 17 patients with dyssynergic defecation in the study was 45.6 years. The colon transit time was prolonged in seven patients (41.2%). In anorectal manometry, 7 patients (41.2%) had improved dyssynergic defecation after dyssynergic defecation. When the relationship between colon transit time and biofeedback therapy was investigated, it was discovered that normal colon transit time was found in 85.7 percent of those who benefited from biofeedback therapy, while slow transit constipation was found in 60% of those who did not. Conclusion: In patients with pre- biofeedback therapy and dyssynergic defecation, colon transit time should be evaluated, and it should be kept in mind that these patients may be resistant to treatment in the case of accompanying slow transit constipation.
排便失调患者结肠转运缓慢及生物反馈治疗的效果
背景:三分之二的排便失调患者结肠转运延迟。因此,排便失调可能与慢传输型便秘有关。目前关于排便失调与慢传输型便秘共存的研究,以及生物反馈治疗在这组患者中的疗效的研究还很缺乏。方法:应用肛门直肠测压和MR排便造影结果对排便异常进行诊断。用24个特殊标记的标记物测量结肠过境时间。所有患者均给予生物反馈治疗。结果:17例排便失调患者的平均年龄为45.6岁。结肠转运时间延长7例(41.2%)。在肛肠测压中,7例(41.2%)患者在排便异常后排便异常改善。当研究结肠运输时间和生物反馈治疗之间的关系时,发现85.7%的受益于生物反馈治疗的患者结肠运输时间正常,而60%的未受益于生物反馈治疗的患者结肠运输时间缓慢便秘。结论:对生物反馈治疗前出现排便失调的患者,应评估结肠转运时间,并注意这类患者在伴有慢转运便秘的情况下可能对治疗产生耐药性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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