Partial Body Weight Support Benefits the Function of Cardiopulmonary and Cardiac Autonomic Nerve in the Early Stage of Heart Failure Rehabilitation

Zhang Wenyu, Jiao Dongdong, L. Beibei, Zhang Xinlei, Zhu Yingzhi, Weng Chuanqing, Wang Xiaohui, Zhu Guangjian
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Abstract

Goal: To investigate the clinical benefits of partial body weight support for the function of Cardiopulmonary and Cardiac autonomic nerve in the early stage of Heart failure rehabilitation. Materials and Methods: We selected 90 patients with heart failure, divided into observation group (n = 45) and control group (n = 45). Both patients had the conventional drug therapy, while the observation group had the partial body weight support additionally within the 3 months treatment period. Serological examination includes brain natriuretic peptide (BNP) and aldosterone. Echocardiography detects left ventricular morphology, cardiac ejection function (EF) and cardiac autonomic nerve function. Minnesota quality of life scale (MHL) evaluates the life quality of the patients. Results: Before any treatment, there is no significant difference of serum brain natriuretic peptide (BNP), aldosterone, cardiac autonomic nerve function and the Minnesota quality of life scale (MHL) (P > 0.05). After treatment, outcome measures declined, including serum brain natriuretic peptide (BNP) and aldosterone (P < 0.01), LVESD and ESV (P < 0.01), LVEDD and EDV (P > 0.05). Outcome measures raised, including SV, CI, EF%, ΔD%. Among them, EF% had significant difference with P value < 0.05, and ΔD% with P value < 0.01. Both LF and HF raised, but LF/HF declined. The Minnesota quality of life scale (MHL) is significantly lower than before. Conclusion: Partial body weight support obviously reduces serum brain natriuretic peptide (BNP) and aldosterone, as well as improves the function of cardiopulmonary and cardiac autonomic nerve of the patients with heart failure, which at last improves the life quality.
部分体重支持在心力衰竭康复早期有利于心肺和心脏自主神经的功能
目的:探讨部分体重支持对心力衰竭康复早期心肺和心脏自主神经功能的临床益处。材料与方法:选择心力衰竭患者90例,分为观察组(n = 45)和对照组(n = 45)。两例患者均采用常规药物治疗,观察组在3个月治疗期内给予部分体重支持。血清学检查包括脑钠肽(BNP)和醛固酮。超声心动图检测左心室形态、心脏射血功能(EF)和心脏自主神经功能。明尼苏达州生活质量量表(MHL)评价患者的生活质量。结果:两组患者治疗前血清脑利钠肽(BNP)、醛固酮、心脏自主神经功能及明尼苏达生活质量量表(MHL)比较,差异均无统计学意义(P < 0.05)。治疗后,包括血清脑钠肽(BNP)和醛固酮在内的预后指标下降(P < 0.05)。结果指标提高,包括SV、CI、EF%、ΔD%。其中EF%差异有统计学意义(P值< 0.05),ΔD%差异有统计学意义(P值< 0.01)。LF和HF均升高,但LF/HF下降。明尼苏达州生活质量量表(MHL)较前显著降低。结论:部分体重支持可明显降低心力衰竭患者血清脑钠肽(BNP)和醛固酮水平,改善心肺和心脏自主神经功能,最终改善患者的生活质量。
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来源期刊
Journal of Medical Imaging and Health Informatics
Journal of Medical Imaging and Health Informatics MATHEMATICAL & COMPUTATIONAL BIOLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
自引率
0.00%
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0
审稿时长
6-12 weeks
期刊介绍: Journal of Medical Imaging and Health Informatics (JMIHI) is a medium to disseminate novel experimental and theoretical research results in the field of biomedicine, biology, clinical, rehabilitation engineering, medical image processing, bio-computing, D2H2, and other health related areas. As an example, the Distributed Diagnosis and Home Healthcare (D2H2) aims to improve the quality of patient care and patient wellness by transforming the delivery of healthcare from a central, hospital-based system to one that is more distributed and home-based. Different medical imaging modalities used for extraction of information from MRI, CT, ultrasound, X-ray, thermal, molecular and fusion of its techniques is the focus of this journal.
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