Oxidative stress in Alzheimer's disease: a selective status report

Abstract

Age has a powerful effect on enhanced susceptibility to cardiovascular diseases, stroke, cognitive impairment and neurodegenerative diseases and a condition of increased oxidative stress status seems to be the link factor. In this paper we briefly reviewed the more recently reports on the role of oxidative stress in aging and age-related diseases with a specific focus on mild cognitive impairment and Alzheimer's disease. The role of antioxidant therapy and/or supplementation and the importance of an antioxidant rich diet are then discussed.