Preoperative Use of Continuous Positive Airway Pressure is related to Postoperative Respiratory Complications in Patients with Obstructive Sleep Apnea Undergoing Endoscopic Sinus Surgery

A. Endo, Y. Kuwabara, K. Yamakawa, D. Sakamaki, A. Suzuki, I. Kondo, Y. Mio, S. Uezono
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Abstract

Backgrounds: Patients with obstructive sleep apnea (OSA) undergoing endoscopic sinus surgery (ESS) are considered at risk of postoperative respiratory complications because postoperative nasal packing often delays resumption of preoperative continuous positive airway pressure (CPAP) therapy. Our hospital implemented a policy in 2011 that all patients with OSA undergoing ESS be admitted to the intensive care unit (ICU) for at least 1 night for postoperative respiratory monitoring. We conducted the present study to evaluate the policy by examining the incidence of postoperative respiratory complications and to identify risk factors for postoperative respiratory complications in these patients. Methods: All patients with OSA scheduled for ESS from 2011 to 2015 were included in this retrospective chart review. Postoperative respiratory complication was defined as decrease of the percutaneous arterial oxygen saturation (SpO2) greater than 3% from each baseline or apnea for more than 20 seconds. We examined the incidence of respiratory complications and conducted multiple logistic regression analysis to determine risk factors for those of complications. Results: A total of 152 patients were analyzed. Postoperative respiratory complications were observed in 27 patients (17.8%) and the minimum value of SpO2 was 84%. None of these patients experienced severe sequelae. Multiple logistic regression analysis showed that preoperative CPAP use was an independent risk factor for postoperative respiratory complications (odds ratio=4.1; 95% CI=1.1–14.7). Conclusion: This retrospective study revealed a relatively high incidence of postoperative respiratory complications after ESS in patients with OSA. Our hospital policy of continuous respiratory monitoring in the ICU for at least 1 night postoperatively appears to be valid for these patients.
内镜鼻窦手术阻塞性睡眠呼吸暂停患者术前持续气道正压通气与术后呼吸并发症相关
背景:阻塞性睡眠呼吸暂停(OSA)患者接受内窥镜鼻窦手术(ESS)被认为有术后呼吸并发症的风险,因为术后鼻腔填塞经常延迟术前持续气道正压(CPAP)治疗的恢复。我院于2011年实施了一项政策,即所有接受ESS治疗的OSA患者均需在重症监护病房(ICU)进行至少1晚的术后呼吸监测。我们进行了本研究,通过检查术后呼吸系统并发症的发生率来评估该政策,并确定这些患者术后呼吸系统并发症的危险因素。方法:回顾性分析2011 - 2015年所有计划进行ESS的OSA患者。术后呼吸并发症定义为经皮动脉血氧饱和度(SpO2)比每次基线下降大于3%或呼吸暂停超过20秒。我们检查了呼吸系统并发症的发生率,并进行了多元logistic回归分析,以确定并发症的危险因素。结果:共分析152例患者。术后出现呼吸系统并发症27例(17.8%),SpO2最小值为84%。这些患者均未出现严重的后遗症。多元logistic回归分析显示术前使用CPAP是术后呼吸系统并发症的独立危险因素(优势比=4.1;95% CI = 1.1 - -14.7)。结论:本回顾性研究显示OSA患者ESS术后呼吸系统并发症发生率较高。我院术后在ICU持续呼吸监测至少1晚的政策似乎对这些患者有效。
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