Prize‐winning abstracts from BSACI/WAO 2022 meeting

Abstract

atop-ics and patients with anaphylaxis. Our findings showed that atop-ics, healthy controls and patients with non- life- threatening allergic reactions had gene polymorphisms consistent with increased activity of angiotensin II. Patients with life- threatening anaphylaxis involving airway angioedema and cardiovascular collapse had gene polymorphisms for low AII activity that could encourage higher eNO activity and shock in anaphylaxis. Single gene analysis, bi- allelic and tri- allelic ensembles of these genes confirmed highly significant differences in gene frequency between these groups. This may offer further understanding of AII and eNO effects on microcirculation in anaphylaxis. life (relevant FAQLQ for specific population) (Penn State Worry Questionnaire) at baseline, 1- and 3- month post- intervention. A total of 129 participants ( n = 33 parents, n = 44 adults and n = 52 children) were recruited and randomized to the intervention or control groups, and 100 ( n = 26 parents, n = 40 adults and n = 34 children) were at the 1- month follow- up. Group CBT reduced impairment in FAQLQ in all populations and reduced levels of worry in the parent group. This study provides encouraging findings regarding the feasibility of brief, online, group CBT in terms of recruitment and retention and a preliminary short- term signal of efficacy on FA quality of life.