Stability of dilute aqueous solutions of 99Tc-HMPAO diastereoisomers

Abstract

A series of dilute solutions of ⁹⁹Tc-HMPAO/^{99 + 99m}Tc-HMPAO diastereoisomers whose concentrations ranged from 10⁻⁸ to 10⁻⁴ M were prepared and the rates of decrease in ⁹⁹Tc-HMPAO diastereoisomers were determined. For the concentration ranges between 10⁻⁸ and 10⁻⁴ M the rates of decrease in their concentration were measured by ITLC and paper chromatography (three strips method). Ultraviolet and visible spectrophotometry was used to determine the rates of concentration changes for 10⁻⁶ ∼ 10⁻⁴ M solutions. The results were compared with previous work.