Protoscolicidal Effects of Bunium Persicum (Boiss) Against Hydatid Cyst Protoscoleces

Abstract

Medicinal plants have been used for treatment of various diseases. The potent scolicidal activity of medicinal plants has been also known. Thus, the current study was conducted to investigate the protoscolicidal effects of Bunium Persicum against hydatid cyst protoscoleces. Protoscoleces were collected from sheep's kidney having hydatid cysts. Five concentrations of B. Persicum essential oil (1, 3, 5, 10 and 15 mg/mL) were investigated for 10, 20, 30 and 60 min. Viability of protoscoleces was confirmed using eosin exclusive test. Regardless of the time, the rate of dead protoscoleces was increased with increasing the essential oil concentrations. The most rates of dead protoscoleces (100 %) were observed in 15 mg/mL from 10 to 60 minutes. On the basis findings this in vitro study, it can be advised B. Persicum essential oil as an effective natural scolicidal agent. Keyword: Bunium Persicum, Hydatid cyst, Protoscoleces, Scolicidal activity.