Study of sensitivity pattern of antimicrobial agent in a tertiary care hospital in tribal area

Abstract

Background: The pharmaceutical companies are flooded with newer and numerous antimicrobial agents. At the same time, bacterial resistance is more challenging and problematic and the biggest threat to Global health of India. Therapeutic failure complicates presentation and sensitivity patterns create a dilemma for the prescriber, and sometimes, the patients respond erratically to antimicrobial agents. This problem will cause 10 million deaths per year by 2050. Culture and sensitivity reports will benefit both the doctors and patients simultaneously. It can affect anyone at any age, and in any country. Therefore, a study was conducted in the new medical college to establish own sensitivity and resistance pattern of this instituition. At the same time, it prevents inappropriate or irrational use of antibiotics, rapid emergency of resistance, adverse drug reaction, higher cost to the patient, longer hospital stays and increases mortality. Aim and Objective: To know the sensitivity and resistance and sensitivity patterns of antimicrobial agents; regulate and promote the appropriate use of antimicrobial agents in PRMMCH, Baripada, Mayurbhanj. Materials and Methods: This prospective study was conducted from May to October 2019 in PRMMCH, Baripada, Department of Pharmacology, in collaboration with the Department of Microbiology. The data were collected from culture sensitivity reports of all positive samples of urine, throat swab, and blood culture from the microbiology department on the prescribed format and finally be analyzed by percentage. Result: The total number of samples with positive culture was 100. Staph aureus was positive in 60%, E. coli 10%, Enterococcus sp and Klebsiella sp 7%, Pseudomonas 6%, Acinetobacter 5%, Citrobacter sp 3%, and Corynebacterium sp 2%. Conclusion: More studies are needed to evaluate the sensitivity and resistant pattern of the microorganisms to different antibiotics from different clinical specimens in this geographical area.