ROSIGLITAZONE, A REPURPOSED DRUG AS ANTICANCER AGENT: A REVIEW

Abstract

Different medicinal products can be used to treat various disorders. Finding promising compounds for both established and new illnesses is the goal of drug development. Finding new therapeutic uses for already-approved, withdrawn-from-use, abandoned, and experimental medications is the process of "drug repurposing." Recently, the medication rosiglitazone (ROSI) was used as an anticancer agent. The status and its application as an anticancer agent are described in the current review. In this review, we outlined the function of ROSI as an anticancer agent and covered a variety of ROSI-related topics, including its molecular mechanism of action, anti-angiogenesis properties, function in oxidative stress and inflammation, function in apoptosis and cell cycle, function in cell migration and invasion, and the use of ROSI in combination therapy with other drug agents.