Pathogenesis and Consequences of Disordered Sleep in PCOS

Clinical Medicine Insights-Reproductive Health Pub Date : 2019-01-01 DOI:10.1177/1179558119871269

Susan Sam, D. Ehrmann

引用次数: 27

Abstract

Polycystic ovary syndrome (PCOS) is a common hormonal disorder that is characterized by hyperandrogenism and menstrual irregularity. Affected women have a high prevalence of insulin resistance and related metabolic complications. The frequency of sleep disturbances appears to be increased in women with PCOS, although most studies so far have included more severely affected obese women with PCOS who are referred to tertiary care clinics and may not represent the general population of women with PCOS. This article provides an overview of sleep disturbances in PCOS with the focus on obstructive sleep apnea (OSA), the most commonly reported sleep disturbance among these women. The pathogenesis and risk factors for OSA in PCOS and its association with metabolic disorders is discussed in detail.

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多囊卵巢综合征患者睡眠障碍的发病机制及后果

多囊卵巢综合征(PCOS)是一种常见的激素失调，其特征是雄激素分泌过多和月经不规律。受影响的妇女胰岛素抵抗和相关代谢并发症的患病率很高。睡眠障碍的频率似乎在多囊卵巢综合征的女性中增加，尽管到目前为止的大多数研究都包括了更严重的多囊卵巢综合征肥胖女性，她们被转诊到三级保健诊所，可能不能代表多囊卵巢综合征女性的一般人群。本文概述了多囊卵巢综合征的睡眠障碍，重点是阻塞性睡眠呼吸暂停(OSA)，这是这些女性中最常见的睡眠障碍。详细讨论了PCOS患者OSA的发病机制、危险因素及其与代谢紊乱的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Medicine Insights-Reproductive Health OBSTETRICS & GYNECOLOGY-

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： Clinical Medicine Insights: Reproductive Health is a peer reviewed; open access journal, which covers all aspects of Reproduction: Gynecology, Obstetrics, and Infertility, spanning both male and female issues, from the physical to the psychological and the social, including: sex, contraception, pregnancy, childbirth, and related topics such as social and emotional impacts. It welcomes original research and review articles from across the health sciences. Clinical subjects include fertility and sterility, infertility and assisted reproduction, IVF, fertility preservation despite gonadotoxic chemo- and/or radiotherapy, pregnancy problems, PPD, infections and disease, surgery, diagnosis, menopause, HRT, pelvic floor problems, reproductive cancers and environmental impacts on reproduction, although this list is by no means exhaustive Subjects covered include, but are not limited to: • fertility and sterility, • infertility and ART, • ART/IVF, • fertility preservation despite gonadotoxic chemo- and/or radiotherapy, • pregnancy problems, • Postpartum depression • Infections and disease, • Gyn/Ob surgery, • diagnosis, • Contraception • Premenstrual tension • Gynecologic Oncology • reproductive cancers • environmental impacts on reproduction, • Obstetrics/Gynaecology • Women''s Health • menopause, • HRT, • pelvic floor problems, • Paediatric and adolescent gynaecology • PID