Cerebellopontine Angle (CPA) Tumors Presenting with Trigeminal Neuralgia (TN): A Study from LRH, Peshawar

Farooq Azam, Hamayun Tahir, Adnan Khaliq
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Abstract

Background/Objective:  The cerebellopontine angle (CPA) is the most prevalent site for brain tumors, accounting for 10% of all cases. CPA tumors can have a direct or indirect pathogenic impact on the auditory nerve and brain stem. The study aimed to quantify the prevalence of cerebellopontine angle tumors in patients with trigeminal neuralgia. Material and Methods:  A cross sections study was conducted and 100 patients were included from the Neurosurgery department of LRH, Peshawar. Magnetic resonance images (MRI) were used to look for CPA tumors. The data on CPA tumors were stratified for age and gender. Suboccipital retromastoid craniectomy was performed. Results:  The mean age of the patients was 43 years. 38 patients were male and 62 were female. CPA tumors were seen in three percent of trigeminal neuralgia patients. There existed a significant difference (p < 0.00001) between the presence and absence of CPA tumors. A maximum number of patients (n = 37) were not having CPA tumors from the age group of 51-60 years. An insignificant association was reported for CPA distribution concerning age and gender. Conclusion:  According to our findings, 3% of trigeminal neuralgia patients had cerebellopontine angle tumors. We urge more investigation and screening of trigeminal neuralgia patients for CPA tumors based on the findings of this study.
以三叉神经痛(TN)为表现的桥小脑角(CPA)肿瘤:白沙瓦LRH地区的研究
背景/目的:桥小脑角(CPA)是脑肿瘤最常见的部位,占所有病例的10%。CPA肿瘤可对听神经和脑干产生直接或间接的致病作用。该研究旨在量化三叉神经痛患者脑桥小脑角肿瘤的患病率。材料与方法:采用横断面研究方法,选取白沙瓦LRH神经外科100例患者。磁共振成像(MRI)用于寻找CPA肿瘤。CPA肿瘤的数据按年龄和性别分层。行枕下乳突后颅骨切除术。结果:患者平均年龄43岁。男性38例,女性62例。三叉神经痛患者中有3%出现CPA肿瘤。存在与不存在CPA肿瘤有显著性差异(p < 0.00001)。51-60岁年龄组中没有CPA肿瘤的患者最多(n = 37)。CPA分布与年龄和性别的关系不显著。结论:三叉神经痛患者中有3%存在桥小脑角肿瘤。我们希望在本研究的基础上对三叉神经痛患者的CPA肿瘤进行更多的调查和筛查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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