Recent Advancement in Ocular Drug Delivery System: A Systematic Review

International Journal For Research in Applied Sciences and Biotechnology Pub Date : 2023-07-10 DOI:10.55544/jrasb.2.3.32

Chavi Mittal, Vandana Sonaji Amle, Roshan Kumar, Prachi Sood, Archna Uniyal, Harjeet Singh

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引用次数: 1

Abstract

Recent scientific and technological advancements have made ophthalmology a top priority for the study of therapeutic products, including the creation, preclinical testing, and clinical evaluation of novel medications, medical devices, and drug-medical device combinations. In order to decrease metabolism and elimination and increase residence time in ocular tissues and compartments, sustained-release drug delivery systems such as liposomes, micelles, nano-emulsions, nanoparticles with colloidal structures, and intraocular implants have been developed. Research is also being conducted in the area of cutting-edge medicines, including those based on gene or cell systems, both of which are considered high-risk products because to their intricate structures. Regarding the definition of drug (medicinal product) and recent changes in regulation, this article reviews recent advancements in ophthalmic drug, gene, and cellular delivery systems and related goods as well as breakthroughs in advanced therapeutic medicinal Products.

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眼部给药系统研究进展综述

最近的科学技术进步使眼科成为治疗产品研究的重中之重，包括新药物、医疗器械和药物-医疗器械组合的创造、临床前测试和临床评估。为了减少代谢和消除，增加在眼组织和腔室中的停留时间，人们开发了脂质体、胶束、纳米乳液、具有胶体结构的纳米颗粒和眼内植入物等缓释药物递送系统。尖端药物领域的研究也在进行，包括那些基于基因或细胞系统的药物，这两种药物都被认为是高风险产品，因为它们的结构复杂。本文就药物(药品)的定义和监管的最新变化，综述了眼科药物、基因和细胞传递系统及其相关产品的最新进展，以及先进治疗药物的突破。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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International Journal For Research in Applied Sciences and Biotechnology

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