Comparative evaluation on clinical efficacy of active oxygen toothpaste with herbal toothpaste in supragingival plaque reduction among gingivitis patients: A randomized controlled trial

Abstract

Context: Gingivitis is a soft-tissue inflammation of the gingiva. It is initiated in the oral cavity by the accumulation of plaque. Among the various plaque control methods, dentifrices play a major role to reduce the microbial load in gingivitis patients. Herbal dentifrice reduces plaque levels and gingival inflammation. In a revolutionary process on dentifrice, BlueM (BM) International has recently introduced the BM dentifrice. Its mechanism of action is to reduce inflammation by controlled delivery of reactive oxygen species to injury sites. Aims: The aim of this study was to compare the clinical efficacy of two commercially available toothpaste, BM, and Dabur Red (DR) in gingivitis patients. Settings and Design: To compare the anti-plaque and anti-gingivitis efficacy of two commercially available toothpaste by measuring gingival, plaque, and bleeding indices in gingivitis patients. Subjects and Methods: A total of 45 patients with chronic gingivitis were included in the study. After oral prophylaxis, they were divided into three groups: Group A, Group B, and Group C who received BM toothpaste, DR toothpaste, and placebo toothpaste, respectively. The clinical parameters were recorded at baseline, 1st, 2nd, and 3rd weeks. Statistical Analysis Used: Data on the gingival index (GI) and plaque index (PI) and bleeding index (BI) were statistically analyzed by the mean and standard deviation between the groups using analysis of variance with Statistical Package for the Social Sciences software (SPSS version 20.0) with a 95% confidence level (P < 0.05). Results: The three groups showed significant reduction (P < 0.05) in PI, GI, and BI from baseline. The BM has more significant mean PI and BI than DR. Conclusions: This study demonstrated that active oxygen toothpaste has comparable anti-plaque and anti-gingivitis efficacies with herbal toothpaste (DR).