Interplay between the cell cycle control machinery and the microtubule network in mouse oocytes

Abstract

The mouse oocyte provides a system in which it is possible to follow the behaviour and activity of the major components of the cell cycle control machinery and their principle cellular targets the chromosomes and the microtubules. In this article, we summarize our present knowledge of the interplay between the cell cycle control machinery and the microtubule network during the meiotic maturation and after activation of the mouse oocytes.