Current pharmacotherapy for obesity

V. A. Aliyeva
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引用次数: 1

Abstract

According to the World Health Organisation (WHO) report, over the last 40 years there was an almost three-fold increase in the prevalence of obesity across the world. During the same period the frequence of obesity in children and adolescents aged 5 to 19 years increased from 1% up to 7%. WHO reported that 65% of the world's population live in countries where overweight and obesity kills more people than underweight. Obesity is associated with various chronic diseases, such as type 2 diabetes, dyslipidemia, and arterial hypertension that increase the risk of disability and death. In patients with obesity, life expectancy is reduced by 15 years compared to individuals with normal body weight. Obesity and associated comorbidities significantly increase healthcare costs. The goals of treatment for obesity should include both weight loss and improvement of glucose and lipid metabolism, hemostasis, etc. The author reviews the current anti-obesity medications that can be used for weight loss.
目前肥胖的药物治疗
根据世界卫生组织(WHO)的报告,在过去的40年里,全世界的肥胖患病率几乎增加了三倍。在同一时期,5至19岁儿童和青少年的肥胖发生率从1%上升到7%。世卫组织报告说,世界上65%的人口生活在超重和肥胖致死人数多于体重不足致死人数的国家。肥胖与各种慢性疾病有关,如2型糖尿病、血脂异常和动脉高血压,这些疾病会增加残疾和死亡的风险。与体重正常的人相比,肥胖患者的预期寿命减少了15年。肥胖和相关的合并症显著增加了医疗保健费用。肥胖的治疗目标应包括减肥和改善糖脂代谢、止血等。作者综述了目前可用于减肥的抗肥胖药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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