Endoscopic Surgery for Pineal Region Tumors

M. Gangemi, F. Maiuri, G. Colella, S. Buonamassa
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引用次数: 75

Abstract

Endoscopic surgery may play an important role in most patients with pineal region tumors. We report our experience with 5 patients treated by a burr hole endoscopic technique. The procedure included in all cases third ventriculostomy for the correction of hydrocephalus, CSF sample for cytology and tumor markers, and tumor biopsy for histological diagnosis. Endoscopic biopsies showed a pineocytoma in two cases, a germinoma in 2 and a low-grade astrocytoma in one. We agree that endoscopic surgery may allow us to select cases requiring a microsurgical approach (medium-sized or large non-germ-cell tumors) from cases to be treated only by irradiation and chemotherapy (germinomas and other non-germ-cell tumors). Then, in some patients with pineal region tumors the endoscopic procedure remains the only surgical treatment. When a direct microsurgical approach is indicated, it may be performed in a non-emergency situation and after correction of the hydrocephalus by endoscopic third ventriculostomy.
松果体区肿瘤的内镜手术
内镜手术可能在大多数松果体区肿瘤患者中发挥重要作用。我们报告我们的经验,5名患者治疗的钻孔内窥镜技术。所有病例均行第三脑室造口术以纠正脑积水,脑脊液取样检查细胞学和肿瘤标志物,肿瘤活检以进行组织学诊断。内镜活检显示2例为松果体细胞瘤,2例为生殖细胞瘤,1例为低度星形细胞瘤。我们同意内窥镜手术可以让我们选择需要显微手术的病例(中型或大型非生殖细胞肿瘤),而不是只需要放疗和化疗的病例(生殖细胞瘤和其他非生殖细胞肿瘤)。然后,在一些患有松果体区肿瘤的患者中,内窥镜手术仍然是唯一的手术治疗方法。当指征直接显微手术入路时,可在非紧急情况下和经内窥镜第三脑室造口术纠正脑积水后进行。
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来源期刊
Minimally Invasive Neurosurgery
Minimally Invasive Neurosurgery 医学-临床神经学
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