Patrick Löber, Bernhard Stimpel, Christopher Syben, A. Maier, H. Ditt, P. Schramm, Boy Raczkowski, A. Kemmling
{"title":"Automatic Thrombus Detection in Non-enhanced Computed Tomography Images in Patients With Acute Ischemic Stroke","authors":"Patrick Löber, Bernhard Stimpel, Christopher Syben, A. Maier, H. Ditt, P. Schramm, Boy Raczkowski, A. Kemmling","doi":"10.2312/vcbm.20171245","DOIUrl":null,"url":null,"abstract":"In case of an ischemic stroke, identifying and removing blood clots is crucial for a successful recovery. We present a novel method to automatically detect vascular occlusion in non-enhanced computed tomography (NECT) images. Possible hyperdense thrombus candidates are extracted by thresholding and connected component clustering. A set of different features is computed to describe the objects, and a Random Forest classifier is applied to predict them. Thrombus classification yields 98.7% sensitivity with 6.7 false positives per volume, and 91.1% sensitivity with 2.7 false positives per volume. The classifier assigns a clot probability ≥ 90% for every thrombus with a volume larger than 100 mm3 or with a length above 23 mm, and can be used as a reliable method to detect blood clots. CCS Concepts •Computing methodologies → Classification and regression trees; •Applied computing → Health care information systems;","PeriodicalId":88872,"journal":{"name":"Eurographics Workshop on Visual Computing for Biomedicine","volume":"27 1","pages":"125-129"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eurographics Workshop on Visual Computing for Biomedicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2312/vcbm.20171245","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
Abstract
In case of an ischemic stroke, identifying and removing blood clots is crucial for a successful recovery. We present a novel method to automatically detect vascular occlusion in non-enhanced computed tomography (NECT) images. Possible hyperdense thrombus candidates are extracted by thresholding and connected component clustering. A set of different features is computed to describe the objects, and a Random Forest classifier is applied to predict them. Thrombus classification yields 98.7% sensitivity with 6.7 false positives per volume, and 91.1% sensitivity with 2.7 false positives per volume. The classifier assigns a clot probability ≥ 90% for every thrombus with a volume larger than 100 mm3 or with a length above 23 mm, and can be used as a reliable method to detect blood clots. CCS Concepts •Computing methodologies → Classification and regression trees; •Applied computing → Health care information systems;