{"title":"Recent Developments in the Synthesis of 1,2,5-Thiadiazoles and 2,1,3-Benzothiadiazoles","authors":"O. Rakitin","doi":"10.1055/s-0039-1690679","DOIUrl":null,"url":null,"abstract":"Abstract The fast-growing interest in 1,2,5-thiadiazoles and their fused analogues including 2,1,3-benzothiadiazoles in recent years as important compounds in materials science and biomedicine has led to great progress in the synthesis of these heterocyclic systems. In this short review, the development of known procedures together with novel reactions is covered. New starting materials, unknown and unexpected transformations for the construction of the thiadiazole ring are emphasized. 1 Introduction 2 Synthesis of Monocyclic 1,2,5-Thiadiazoles 2.1 From 1,2-Diamines, vic-Dioximes and Related Compounds 2.2 From Alkyl Aryl (Hetaryl) Ketoximes and Tetrasulfur Tetranitride 2.3 By Condensation Reactions 2.4 From Other Heterocycles 3 Synthesis of Fused 1,2,5-Thiadiazoles 3.1 From ortho-Phenylenediamines and Related Compounds 3.2 From ortho-Aminonitroso and ortho-Aminonitro Derivatives 3.3 By Condensation Reactions 3.4 By Chalcogen Exchange in 1,2,5-Oxa- and 1,2,5-Selenadiazoles 3.5 Miscellaneous Methods 4 Conclusions","PeriodicalId":49451,"journal":{"name":"Synthesis-Stuttgart","volume":null,"pages":null},"PeriodicalIF":2.2000,"publicationDate":"2019-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"20","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Synthesis-Stuttgart","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1055/s-0039-1690679","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 20
Abstract
Abstract The fast-growing interest in 1,2,5-thiadiazoles and their fused analogues including 2,1,3-benzothiadiazoles in recent years as important compounds in materials science and biomedicine has led to great progress in the synthesis of these heterocyclic systems. In this short review, the development of known procedures together with novel reactions is covered. New starting materials, unknown and unexpected transformations for the construction of the thiadiazole ring are emphasized. 1 Introduction 2 Synthesis of Monocyclic 1,2,5-Thiadiazoles 2.1 From 1,2-Diamines, vic-Dioximes and Related Compounds 2.2 From Alkyl Aryl (Hetaryl) Ketoximes and Tetrasulfur Tetranitride 2.3 By Condensation Reactions 2.4 From Other Heterocycles 3 Synthesis of Fused 1,2,5-Thiadiazoles 3.1 From ortho-Phenylenediamines and Related Compounds 3.2 From ortho-Aminonitroso and ortho-Aminonitro Derivatives 3.3 By Condensation Reactions 3.4 By Chalcogen Exchange in 1,2,5-Oxa- and 1,2,5-Selenadiazoles 3.5 Miscellaneous Methods 4 Conclusions
期刊介绍:
SYNTHESIS is an international full-paper journal devoted to the advancement of the science of chemical synthesis. It covers all fields of organic chemistry involving synthesis, including catalysis, organometallic, medicinal, biological, and photochemistry, but also related disciplines. SYNTHESIS provides dependable research results with detailed and reliable experimental procedures and full characterization of all important new products as well as scientific primary data.