Actualización de los valores normales de los parámetros bioquímicos y de la osmolaridad del plasma seminal

Abstract

Objective

An updated review is presented on some biochemistry and osmolality reference values in seminal plasm. These values were also compared with the seminogram values.

Material and methods

A study was made of 37 normal seminal plasma from patients attending the Sterility and Assisted Reproduction Service of our Hospital. The mean patient age was 34.4 years, with a 95% confidence interval (CI) from 32.5 to 36.3. The reference values of the biochemical parameters were obtained using a Beckman-Coulter AU 5800 chemistry analyser and a Cobas-Mira II analyser. Seminal plasma osmolality was measured using an Advanced Osmometer 2020 3MO.

Results

The mean concentration for the biochemical parameters were: total proteins 3.87 g/dl (95% CI; 3.5-4.3), albumin 0.67 g/dl (95% CI; 0.52-0.82), glucose 6.11 mmol/l (95% CI; 5.35-6.67), fructose 13.5 mmol/l (95% CI; 11.7-15.3), sodium 122 mmol/l (95% CI; 119-125), potassium 23 mmo/l (95% CI; 22-25), choride 41 mmol/l (95% CI; 37-44), calcium 27.1 mg/dl (95% CI; 23.7-30.5), magnesium 10.9 mg/dl (95% CI; 9.18-12.7), phosphorous 68.1 mg/dl (95% CI; 58.6-77.6), and zinc 1.5 mmol/l (95% CI; 1.25-1.73). The reference values for the calculated osmolality were 422 mOsmol/Kg (95% CI; 407- 439). Na, K, Ca, Mg, and Zn parameters showed a significant positive correlation with the quality semen criteria (sperm concentration, motility, and sperm morphology/ejaculate)

Conclusions

An updated review is presented on reference values of some biochemical parameters in seminal plasma using new automated analysers. This may be useful to study the relationship between different pathologies and the biochemical and osmolality values in seminal plasma. A significant correlation has been calculated between these biochemical parameters and the quality semen values.