{"title":"Anticancer Drug Combinations, Studies from Different Pathways","authors":"D. Lu","doi":"10.4172/2168-9296.1000166","DOIUrl":null,"url":null,"abstract":"Most cancer therapies are seldom effective by single anticancer drug based on multiple genetic alterations and molecular abnormalities. Anticancer drug combination utilities need to transform from empirical to science-guided enterprises. This editorial offers the background knowledge of drug combination therapies by mathematical enquiry. Possible future landscapes and drawbacks of current cancer drug combinative therapy are addressed and speculated.","PeriodicalId":9775,"journal":{"name":"Cell & developmental biology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"14","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell & developmental biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2168-9296.1000166","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 14
Abstract
Most cancer therapies are seldom effective by single anticancer drug based on multiple genetic alterations and molecular abnormalities. Anticancer drug combination utilities need to transform from empirical to science-guided enterprises. This editorial offers the background knowledge of drug combination therapies by mathematical enquiry. Possible future landscapes and drawbacks of current cancer drug combinative therapy are addressed and speculated.