Duane G. Wenzel, Ivens A. Siegel, Robert E. Nichols
{"title":"A System for Measuring Contractions of the Rat Ventricle Strip*","authors":"Duane G. Wenzel, Ivens A. Siegel, Robert E. Nichols","doi":"10.1002/jps.3030490914","DOIUrl":null,"url":null,"abstract":"<div><p>A system is described for the quantitative measurement of the contractions of the electrically driven rat ventricle strip. The apparatus includes the components of the transducer-amplifier-recording system as well as a simplified muscle-holder and electrode assembly. As normally employed, the system accurately measures semi-isometric (>0.025 mm. displacement) muscle contractions at a stimulus frequency of four per second. It may also be employed at other frequencies and for moderate isotonic contractions as well as for gas displacement.</p></div>","PeriodicalId":100839,"journal":{"name":"Journal of the American Pharmaceutical Association (Scientific ed.)","volume":"49 9","pages":"Pages 614-616"},"PeriodicalIF":0.0000,"publicationDate":"1960-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/jps.3030490914","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the American Pharmaceutical Association (Scientific ed.)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0095955315363150","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A system is described for the quantitative measurement of the contractions of the electrically driven rat ventricle strip. The apparatus includes the components of the transducer-amplifier-recording system as well as a simplified muscle-holder and electrode assembly. As normally employed, the system accurately measures semi-isometric (>0.025 mm. displacement) muscle contractions at a stimulus frequency of four per second. It may also be employed at other frequencies and for moderate isotonic contractions as well as for gas displacement.