Bone augmentation in rat by highly porous β-TCP scaffolds with different open-cell sizes in combination with fibroblast growth factor-2

H. Miyaji, Hiroyuki Yokoyama, Yuta Kosen, H. Nishimura, Kazuyasu Nakane, Saori Tanaka, Kaori Otani, Kana Inoue, Asako Ibara, Izumi Kanayama, Takashi Yoshida, Kosuke Ogawa, Erika Nishida, M. Kawanami
{"title":"Bone augmentation in rat by highly porous β-TCP scaffolds with different open-cell sizes in combination with fibroblast growth factor-2","authors":"H. Miyaji, Hiroyuki Yokoyama, Yuta Kosen, H. Nishimura, Kazuyasu Nakane, Saori Tanaka, Kaori Otani, Kana Inoue, Asako Ibara, Izumi Kanayama, Takashi Yoshida, Kosuke Ogawa, Erika Nishida, M. Kawanami","doi":"10.11223/JARDE.10.172","DOIUrl":null,"url":null,"abstract":"172 INTRODUCTION In tissue engineering therapy, proliferation and migration of regenerated cells should be facilitated to reform functional tissue following surgical treatment. For this objective, three-dimensional scaffolds, an important element of tissue engineering, are being extensively studied for application in regenerative procedures. Bioceramic materials have mechanical, biocompatible and osteoconductive properties for use as scaffolds in various artificially synthesized types and forms, e.g., bioactive glass , hydroxyapatite (HA) 2, , tricalcium phosphate (TCP) 3, 4 and composites 5, . β-TCP presents a greater biodegradable effect in comparison with HA . The β-TCP scaffold in combination with growth factors has been shown to Bone Augmentation in Rat by Highly Porous β-TCP Scaffolds with Different Open-cell Sizes in Combination with Fibroblast Growth Factor-2","PeriodicalId":16589,"journal":{"name":"Journal of oral tissue engineering","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2013-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of oral tissue engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11223/JARDE.10.172","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3

Abstract

172 INTRODUCTION In tissue engineering therapy, proliferation and migration of regenerated cells should be facilitated to reform functional tissue following surgical treatment. For this objective, three-dimensional scaffolds, an important element of tissue engineering, are being extensively studied for application in regenerative procedures. Bioceramic materials have mechanical, biocompatible and osteoconductive properties for use as scaffolds in various artificially synthesized types and forms, e.g., bioactive glass , hydroxyapatite (HA) 2, , tricalcium phosphate (TCP) 3, 4 and composites 5, . β-TCP presents a greater biodegradable effect in comparison with HA . The β-TCP scaffold in combination with growth factors has been shown to Bone Augmentation in Rat by Highly Porous β-TCP Scaffolds with Different Open-cell Sizes in Combination with Fibroblast Growth Factor-2
不同开孔细胞大小的高孔β-TCP支架联合成纤维细胞生长因子-2对大鼠骨的增强作用
在组织工程治疗中,应促进再生细胞的增殖和迁移,以在手术治疗后改造功能组织。为此,三维支架作为组织工程的一个重要组成部分,正在广泛研究其在再生过程中的应用。生物陶瓷材料具有机械、生物相容性和骨导电性,可用于各种人工合成类型和形式的支架,如生物活性玻璃、羟基磷灰石(HA) 2、磷酸三钙(TCP) 3、4和复合材料5、。与HA相比,β-TCP具有更强的生物降解效果。不同开孔细胞大小的高孔β-TCP支架与成纤维细胞生长因子-2联合使用后,已显示出β-TCP支架与生长因子联合使用对大鼠骨增强的作用
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信