A Review on Remdesivir: An Alternative Antiviral Drug to Fight against COVID-19

Abstract

A coronavirus infection that was discovered in early 2019 has already hampered the world’s purpose so far. The number of infectious cases has grown worldwide to 35 lakhs and so the outbreak has been described as a pandemic by the planet’s health organization, but there have not been any “specific drugs” or vaccines available to date. Relevant reports have identified a novel coronavirus with 80% homology with SARS. So there are few indications available when other countries are using the antiviral drug Remdesivir. The specific antiviral drug regimen for the treatment of patients with acute coronavirus disease 2019 (COVID-19) has not been proven. Remdecivir (GS-5734), a nucleoside analog product, has inhibitory effects on pathogenic animal and human coronaviruses including acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro , and Middle East respiratory syndrome, NiR. -1, and SARS-CoV-2 replication in animal models.