Survivorship Endpoints in Pet Dogs with Naturally Occurring Cancer as Models for Human Cancer

Mairin Miller, S. Stewart, K. Wendelburg, F. Lew, John Berg, Arata Matsuyama, A. Mutsaers, S. Kahn, Craig Clifford, Gary Clark, C. Khanna
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Abstract

Endpoints in Pet Dogs with Naturally Occurring Cancer as Models for Human Cancer. Abstract Pet dogs with cancer have been valuable models for human cancer drug development (Comparative Oncology). Despite strong similarities, the false perception that survivorship in veterinary cancer patients does not exist creates a challenge in translation of efficacy signals, from dog studies to humans, and constrains innovation in veterinary oncology. Until now veterinary oncology has been unique in its focus on the median when reporting
宠物狗自然发生的癌症作为人类癌症模型的生存终点
宠物狗自然发生癌症的终点作为人类癌症的模型。患有癌症的宠物狗是人类癌症药物开发的有价值的模型(比较肿瘤学)。尽管有很强的相似性,但认为兽医癌症患者不存在存活的错误看法,给从犬类研究到人类研究的疗效信号转化带来了挑战,并限制了兽医肿瘤学的创新。到目前为止,兽医肿瘤学在报告时一直专注于中位数
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