The association between serum ferritin and blood pressure in adult women: a large cross-sectional study

IF 1.5 4区医学 Q3 PERIPHERAL VASCULAR DISEASE

Clinical and Experimental Hypertension Pub Date : 2022-05-26 DOI:10.1080/10641963.2022.2079667

Andong He, Xiaofeng Yang, Yuzhen Ding, Lu Sun, M. Shi, Ruiman Li

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引用次数: 2

Abstract

ABSTRACT Background Studies on the relationships between ferritin and blood pressure remain limited, especially in adult women. The aim of the present study was to investigate the associations between serum ferritin and blood pressure among adult women. Methods Using the National Health and Nutrition Examination Survey, a cross-sectional study, including 5521 adult women, was performed. Weighted multivariate regressions, subgroup analyses, threshold effect analyses, and sensitivity analysis were used. Results The authors found that serum ferritin was independently and positively correlated to diastolic blood pressure (DBP), and this positive correlation kept present among women who are 26–30 years old, non-pregnant women, Mexican American women, and women of other races in the subgroup analyses. Additionally, no significant association was found between serum ferritin and systolic blood pressure (SBP), except in women aged 26–30, Mexican American women, and women of other races. In pregnant women, the association between serum ferritin and SBP was an inverted U-shaped curve with an inflection point at 39.5 ng/mL. Conclusions The authors demonstrated that serum ferritin was positively correlated to DBP in adult women, which may provide a novel reference for clinical management.

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成年女性血清铁蛋白与血压之间的关系:一项大型横断面研究

背景关于铁蛋白与血压之间关系的研究仍然有限，特别是在成年女性中。本研究的目的是调查成年女性血清铁蛋白与血压之间的关系。方法采用全国健康与营养调查，对5521名成年妇女进行横断面研究。采用加权多元回归、亚组分析、阈值效应分析和敏感性分析。结果作者发现血清铁蛋白与舒张压(DBP)独立且正相关，并且在亚组分析中，这种正相关在26-30岁妇女、非孕妇、墨西哥裔美国妇女和其他种族妇女中保持存在。此外，除了26-30岁的女性、墨西哥裔美国女性和其他种族的女性外，血清铁蛋白与收缩压(SBP)之间没有明显的关联。在孕妇中，血清铁蛋白与收缩压呈倒u型曲线，拐点为39.5 ng/mL。结论血清铁蛋白与成年女性舒张电位呈正相关，可为临床治疗提供新的参考。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and Experimental Hypertension 医学-外周血管病

CiteScore

3.90

自引率

0.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Clinical and Experimental Hypertension is a reputable journal that has converted to a full Open Access format starting from Volume 45 in 2023. While previous volumes are still accessible through a Pay to Read model, the journal now provides free and open access to its content. It serves as an international platform for the exchange of up-to-date scientific and clinical information concerning both human and animal hypertension. The journal publishes a wide range of articles, including full research papers, solicited and unsolicited reviews, and commentaries. Through these publications, the journal aims to enhance current understanding and support the timely detection, management, control, and prevention of hypertension-related conditions. One notable aspect of Clinical and Experimental Hypertension is its coverage of special issues that focus on the proceedings of symposia dedicated to hypertension research. This feature allows researchers and clinicians to delve deeper into the latest advancements in this field. The journal is abstracted and indexed in several renowned databases, including Pharmacoeconomics and Outcomes News (Online), Reactions Weekly (Online), CABI, EBSCOhost, Elsevier BV, International Atomic Energy Agency, and the National Library of Medicine, among others. These affiliations ensure that the journal's content receives broad visibility and facilitates its discoverability by professionals and researchers in related disciplines.