Genmab Further Validates its DuoBody™ Technology with Janssen Biotech Agreement

Heather Cartwright
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Abstract

Genmab has made further progress with its DuoBody™ technology platform by agreeing to collaborate with Johnson & Johnson’s Janssen Biotech to create and develop bispecific antibodies against multiple disease targets. Janssen will fund all research and Genmab will receive US$3.5 M upfront plus potential milestone and licence payments of up to US$175 M for each product successfully developed from the collaboration as well as royalties on sales of any commercialised products. Amgen’s US$1.16 B acquisition of Micromet in March 2012 fuelled industry interest in bispecific antibody technologies.
Genmab与Janssen Biotech达成协议,进一步验证其DuoBody™技术
近日,Genmab公司与强生旗下的杨森生物技术公司(Janssen Biotech)达成合作协议,在开发针对多种疾病靶点的双特异性抗体方面取得了进一步进展。杨森将为所有研究提供资金,Genmab将获得350万美元的预付款,再加上从合作中成功开发的每种产品的潜在里程碑和高达1.75亿美元的许可付款,以及任何商业化产品销售的版税。2012年3月,安进公司以11.6亿美元收购了Micromet公司,激发了业界对双特异性抗体技术的兴趣。
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