Effects of mineral trioxide aggregate and platelet-rich fibrin on histological results of direct pulp capping in dogs

IF 0.5 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Giornale Italiano di Endodonzia Pub Date : 2020-01-01 DOI:10.32067/10.32067/GIE.2021.35.01.01

Bahareh Aghamohammadi Ameghani, A. Tavakoli, M. H. Tabatabaei, S. Valizadeh

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引用次数: 1

Abstract

Aim: This study aimed to compare the effects of mineral trioxide aggregate (MTA) and platelet-rich fibrin (PRF) on histological results of direct pulp capping (DPC) in dogs. Methodology: In this animal study, 36 class V cavities were prepared in the incisors of adult healthy mixed-breed dogs. The teeth were then randomly divided into three groups. No material was placed in the control teeth. MTA and PRF were placed on the exposure site in groups 2 and 3, respectively. After 2 months, the teeth were extracted under general anesthesia and were histological analyzed regarding inflammation, calcified bridge formation and necrosis. Data were analyzed using non-parametric Kruskal-Wallis test. Pairwise comparisons were made using the Mann-Whitney U test. Results: There are no statistically significant differences in terms of pulp inflammation, dentinal bridge formation and necrosis among the treatment groups capping with MTA and PRF. (P Value >0.05), however, PRF and MTA were the same in all parameters, these groups were both significantly superior to the control group. Conclusion: Within the limitations of this study, PRF can be used for DPC as an alternative to MTA.

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三氧化二矿聚集体和富血小板纤维蛋白对狗直接髓盖的组织学结果的影响

目的:比较三氧化矿物聚集体(MTA)和富血小板纤维蛋白(PRF)对狗直接髓盖(DPC)组织学结果的影响。方法:本动物实验在健康成年杂交犬的门牙上制备了36个V类空腔。然后这些牙齿被随机分成三组。对照牙内未放置任何材料。2组和3组分别在暴露部位放置MTA和PRF。2个月后全麻拔牙，观察组织炎症、钙化桥形成及坏死情况。数据分析采用非参数Kruskal-Wallis检验。两两比较采用Mann-Whitney U检验。结果:MTA盖顶组与PRF盖顶组在牙髓炎症、牙本质桥形成和坏死方面差异无统计学意义。(P值>0.05)，但各参数PRF、MTA均无显著差异，且均显著优于对照组。结论:在本研究的局限性内，PRF可以作为MTA的替代方法用于DPC。

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来源期刊

Giornale Italiano di Endodonzia DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

0.90

自引率

25.00%

发文量

审稿时长

24 weeks

期刊介绍： The Giornale Italiano di Endodonzia was founded in 1987 and is the official journal of the Italian Society of Endodontics (SIE). It is a peer-reviewed journal publishing original articles on clinical research and/or clinical methodology, case reports related to Endodontics. The Journal evaluates also contributes in restorative dentistry, dental traumatology, experimental pathophysiology, pharmacology and microbiology dealing with Endodontics.