Significance of Stem Cells in Forensic Dentistry

B. Karthika, S. Nisa
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Abstract

In forensic point of view and for genetic study, biological samples collected at a crime scene serve as a significant tool, in order to resolve crimes by identifying the person. In some scenarios, individual identification gets masked by chimera persons, where the chimera person cells will have different DNA. The use of biological traces which are recorded by a person’s touch while handling items raises the chance of forensic study system. Therefore, DNA profiling can be obtained from items that were touched, which inturn becomes an useful means for forensic mode of investigation. Chimerism investigations are recognized processes to examine the condition of Hematopoietic Stem Cell Transplantation (HSCT) to analyze peripheral blood and recipient’s bone marrow samples for non-malignant and malignant hematologic diseases. In adults, ectomesenchymal cells identified in oral and maxillofacial tissues are promising for future dental stem cell therapies, because the oral tissues area rich source for stem cells. Dental stem cells have various expressive profiles and exist in specific niches. Apart from these applications, this review article highlights dental stem cells significances in forensic dental investigations.
干细胞在法医牙医学中的意义
从法医和遗传学的角度来看,在犯罪现场收集的生物样本是通过识别人来解决犯罪的重要工具。在某些情况下,嵌合体掩盖了个体识别,嵌合体细胞将具有不同的DNA。生物痕迹的使用是通过一个人在处理物品时的触摸记录的,这增加了法医研究系统的可能性。因此,DNA分析可以从被接触的物品中获得,从而成为法医调查模式的有用手段。嵌合检查是检查造血干细胞移植(HSCT)状况的公认过程,用于分析外周血和受体骨髓样本,以诊断非恶性和恶性血液疾病。在成人中,口腔和颌面组织中发现的外充质细胞是未来牙科干细胞治疗的希望,因为口腔组织是干细胞的丰富来源。牙干细胞具有多种表达谱,存在于特定的小生境中。除了这些应用之外,这篇综述文章还强调了牙干细胞在法医牙科调查中的意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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