R. Conder, Leon H. Chew, Fisal Elstone, Marianne Lankhorst, Adam Añonuevo, S. Simmini, W. Chang, A. Eaves, T. Thomas, S. Louis
{"title":"Organoid culture systems: Products supporting one of the biggest revolutions in biological research","authors":"R. Conder, Leon H. Chew, Fisal Elstone, Marianne Lankhorst, Adam Añonuevo, S. Simmini, W. Chang, A. Eaves, T. Thomas, S. Louis","doi":"10.4081/bse.2019.102","DOIUrl":null,"url":null,"abstract":"Organoids are stem cell-derived structures that are generated in three-dimensional tissue culture. They are unique since they exhibit a high degree of self-organization and differentiation, and thus recapitulate many of the features of the tissues from which they were derived. Because of this, organoids are now firmly established as an essential tool in medical research, and have the potential to drastically reduce the number of animals required for experimentation.","PeriodicalId":89077,"journal":{"name":"Annual ORNL Biomedical Science and Engineering Center Conference. ORNL Biomedical Science and Engineering Center Conference","volume":"335 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annual ORNL Biomedical Science and Engineering Center Conference. ORNL Biomedical Science and Engineering Center Conference","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4081/bse.2019.102","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Organoids are stem cell-derived structures that are generated in three-dimensional tissue culture. They are unique since they exhibit a high degree of self-organization and differentiation, and thus recapitulate many of the features of the tissues from which they were derived. Because of this, organoids are now firmly established as an essential tool in medical research, and have the potential to drastically reduce the number of animals required for experimentation.