Squamous cell lung carcinoma with surrounding pure nonmucinous bronchioloalveolar carcinoma (BAC)

Shuichi Yano , Kanako Kobayashi , Yoshiyuki Tokuda , Hirokazu Touge , Toshikazu Ikeda , Shigenori Ishikawa , Hiroyasu Takeyama , Kunio Araki
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引用次数: 1

Abstract

Bronchioloaveolar cell carcinoma (BAC) was defined by the WHO in 1999 to be a subtype of adenocarcinoma with a pure bronchioloalveolar growth pattern showing no evidence of stromal, vascular, or pleural invasion [Travis WD, Colby TV, Conin B, et al. Bronchioloalveolar carcinoma. In: Sobin LH, editor. WHO international histological classification of tumors, 3rd ed. Copenhagen, Denmark: Springer; 1999. p. 34–8]. Although there were some reports that BAC was presented together with squamous cell carcinoma, this is the first report that it might be transformed from surrounding pure nonmucinous BAC. Physicians should be aware that pure BAC could transform to squamous cell carcinoma, and that such cases might not respond to gefitinib.

肺癌伴纯非粘液性细支气管肺泡癌(BAC)
1999年WHO将细支气管肺泡细胞癌(BAC)定义为腺癌的一种亚型,其表现为纯粹的细支气管肺泡生长模式,没有基质、血管或胸膜浸润的证据[Travis WD, Colby TV, Conin B,等]。支气管肺泡癌。编辑:Sobin LH。WHO国际肿瘤组织学分类,第三版。哥本哈根,丹麦:施普林格;1999. p。34-8]。虽然有一些报道称BAC与鳞状细胞癌一起出现,但这是第一次报道它可能是从周围的纯非粘液性BAC转化而来的。医生应该意识到纯BAC可能转变为鳞状细胞癌,而这种情况可能对吉非替尼没有反应。
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