Lichen Sclerosis Involving Vagina and Cervix

{"title":"Lichen Sclerosis Involving Vagina and Cervix","authors":"","doi":"10.24966/rmgo-2574/100026","DOIUrl":null,"url":null,"abstract":"Background: Lichen Sclerosus (LS) is commonly a disease of the vulva usually seen in postmenopausal women. It presents as an atrophic white patchy area in a figure of 8 pattern. Fissuring is also commonly seen because of skin fragility. It is diagnosed by history and clinical assessment but usually confirmed with a biopsy. There is no cure for LS. The mainstay of treatment is potent topical steroids and in some cases oral immunosuppressive medicines may also be used. It is important to acknowledge the role of laser surgery in treat ing the sequel of scarring secondary to LS. Because LS is associ ated with increased risk of squamous cell carcinoma in women with genital involvement, it is important for those affected to have lifelong screening examinations as well as continued treatment to keep the disorder under control. Only six cases of vaginal LS, but no cases of cervical LS exist in the literature. Case: The authors present a case of a postmenopausal lady pre senting with a 30 year history of prolapse and a urinary tract infec tion. Examination revealed, 3rd degree utero-vaginal prolapse with widespread whitish discoloration of anterior, posterior and lateral vaginal walls, which also included the cervix. After counseling the patient and presenting her with the options for treatment, she chose to have the gellhorn pessary inserted in the outpatient clinic. Vaginal and cervical biopsy was taken under local anesthesia and histology confirmed LS. Patient was followed up in clinic and prescribed ste -roids. Conclusion: LS involving the vagina and cervix is a rare occurrence, unlike lichen planus, which can present in the vagina. Long term untreated genital prolapse may have a role in the development. As the occurrence of this condition is rare, each case should be treated individually and ideally after discussion in MDT meeting.","PeriodicalId":87233,"journal":{"name":"Clinical obstetrics, gynecology and reproductive medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical obstetrics, gynecology and reproductive medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24966/rmgo-2574/100026","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract

Background: Lichen Sclerosus (LS) is commonly a disease of the vulva usually seen in postmenopausal women. It presents as an atrophic white patchy area in a figure of 8 pattern. Fissuring is also commonly seen because of skin fragility. It is diagnosed by history and clinical assessment but usually confirmed with a biopsy. There is no cure for LS. The mainstay of treatment is potent topical steroids and in some cases oral immunosuppressive medicines may also be used. It is important to acknowledge the role of laser surgery in treat ing the sequel of scarring secondary to LS. Because LS is associ ated with increased risk of squamous cell carcinoma in women with genital involvement, it is important for those affected to have lifelong screening examinations as well as continued treatment to keep the disorder under control. Only six cases of vaginal LS, but no cases of cervical LS exist in the literature. Case: The authors present a case of a postmenopausal lady pre senting with a 30 year history of prolapse and a urinary tract infec tion. Examination revealed, 3rd degree utero-vaginal prolapse with widespread whitish discoloration of anterior, posterior and lateral vaginal walls, which also included the cervix. After counseling the patient and presenting her with the options for treatment, she chose to have the gellhorn pessary inserted in the outpatient clinic. Vaginal and cervical biopsy was taken under local anesthesia and histology confirmed LS. Patient was followed up in clinic and prescribed ste -roids. Conclusion: LS involving the vagina and cervix is a rare occurrence, unlike lichen planus, which can present in the vagina. Long term untreated genital prolapse may have a role in the development. As the occurrence of this condition is rare, each case should be treated individually and ideally after discussion in MDT meeting.
包括阴道和子宫颈的地衣硬化
背景:硬化苔藓(LS)是一种常见于绝经后妇女的外阴疾病。它表现为萎缩的白色斑驳区域,呈8字形。由于皮肤脆弱,裂裂也很常见。它通过病史和临床评估诊断,但通常通过活检确诊。目前还没有治愈LS的方法。主要的治疗方法是有效的局部类固醇,在某些情况下也可以使用口服免疫抑制药物。认识到激光手术在治疗LS继发瘢痕后遗症中的作用是很重要的。由于LS与累及生殖器的女性患鳞状细胞癌的风险增加有关,因此对那些受影响的人进行终身筛查检查以及持续治疗以控制疾病是很重要的。文献中仅有6例阴道LS,未见宫颈LS。案例:作者提出一个绝经后的妇女提出30年脱垂和尿路感染的历史。检查发现,子宫阴道三度脱垂,阴道前、后、外侧壁广泛发白,包括宫颈。在咨询了病人并向她介绍了治疗方案后,她选择在门诊诊所插入盖尔霍恩子宫托。局部麻醉下行阴道和宫颈活检,组织学证实为LS。临床随访并给予药物治疗。结论:LS累及阴道及子宫颈少见,不像扁平苔藓可累及阴道。长期未经治疗的生殖器脱垂可能在发展中起作用。由于这种情况的发生是罕见的,每个病例都应该单独治疗,最好在MDT会议上讨论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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