Comparison of butorphanol and clonidine for control of intraoperative shivering under spinal anaesthesia at a tertiary hospital

S. Nandkumar, Vijay Kumar Katla
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Abstract

Background: Spinal anaesthesia is world-widely used as a safe anaesthetic technique elective as well as emergency surgeries. Spinal anesthesia is known to decrease the vasoconstriction and shivering thresholds leading to shivering. In present study we compared butorphanol and clonidine for control of intraoperative shivering after spinal anaesthesia at our tertiary hospital. Material and Methods: Present study was a comparative, clinical, interventional study conducted in patients aged between 18-68 years, of either sex, had American Society of Anaesthesiologists (ASA) physical status I/II, scheduled for elective lower abdominal surgeries under subarachnoid block. 60 patients were randomly allocated into group B (n= 30, received sintravenous bolus butorphanol) and group C (n= 30, received intravenous bolus of clonidine). Results: 60 patients were randomly allocated into group B (n= 30, received butorphanol) and group C (n= 30, received clonidine). We compared age (years), weight (Kg), BMI(Kg/m2), Gender (Male/Female) and ASA grade between both groups and no statistically significant difference was noted among them. We noted earlier onset of sensory as well as motor block and prolonged duration of sensory as well as motor block in butorphanol group as compared to clonidine group and difference was statistically significant. Incidence of shivering was more in clonidine group as compared to butorphanol group and difference was statistically significant. Also hypotension was more in clonidine group as compared to butorphanol group and difference was statistically significant. Similar incidence of bradycardia was noted in both groups. Conclusion: We noted that butorphanol is more effective than clonidine in the treatment of shivering because of its faster onset, lesser recurrence rate, and less complications reported.
布托啡诺与可乐定对三甲医院脊柱麻醉术中寒战的控制效果比较
背景:脊髓麻醉作为一种安全的麻醉技术在世界范围内广泛使用,也可用于急诊手术。已知脊髓麻醉可以降低血管收缩和导致颤抖的寒战阈值。在本研究中,我们比较了布托啡诺和克拉定在控制脊柱麻醉后术中寒战中的作用。材料和方法:本研究是一项对比性、临床、介入性研究,患者年龄在18-68岁之间,男女均可,具有美国麻醉学会(ASA)身体状态I/II,计划在蛛网膜下腔阻滞下择期进行下腹手术。60例患者随机分为B组(n= 30,静脉滴注丁托啡诺)和C组(n= 30,静脉滴注可乐定)。结果:60例患者随机分为B组(n= 30,给予布托啡诺)和C组(n= 30,给予可乐定)。比较两组间年龄(years)、体重(Kg)、BMI(Kg/m2)、性别(Male/Female)、ASA分级,差异无统计学意义。与可乐定组相比,布托啡诺组感觉和运动阻滞的发病时间更早,感觉和运动阻滞的持续时间更长,差异有统计学意义。可乐定组寒战发生率高于布托啡诺组,差异有统计学意义。可乐定组低血压发生率高于布托啡诺组,差异有统计学意义。两组的心动过缓发生率相似。结论:我们注意到布托啡诺比可乐定治疗寒战更有效,因为它起效更快,复发率更低,并发症报告更少。
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