Carbapenem resistant Acinetobacter baumannii in ICU patients in a tertiary care hospital: A retrospective study highlighting their demographic and clinical profile, impact on ICU stay and mortality

Abstract

: was considered as a leading cause of nosocomial respiratory infection and bacteremia in many hospitals all over the world. However, there was a still a debates whether colonization and/or infection with , increases morbidity and mortality independently of the effect of other risk factors.Aim of the study was to isolate among ICU patients, to detect carbapenem resistant among ICU patients with infections and to determine specific risk factors and outcome of the infections due to CRAB isolates. : A retrospective study was carried out at Vydehi Institute of Medical Sciences and RC in Bangalore, in the ICU department from June 2021 to May 2022.Among all the patients carbapenem resistance was detected more in patients above 60 years of age, males were predominant than females, most of the patients were on ventilation and in sepsis and mortality rate was high with the increased duration of ICU stays. is a highly prevalent microorganism among ICU patients, while its potential to acquire resistance toward commonly used antibiotics represents it as a grave threat to the health care industry. Therefore, signifying the need for its regular monitoring in the health care setups. VAP due to CRAB and excess use of intravascular devices are the most important risk factors for CRAB bacteremia in our ICU. Early implementation of appropriate antimicrobial therapy, particularly in critically ill ICU patients with Carbapenem resistant infections, with two or more co morbidities, can be crucial for survival.