National Prevalence and Correlates of Autism: A Lebanese Cross-Sectional Study

D. Saab, M. Chaaya, R. Boustany
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引用次数: 10

Abstract

Background: There is a lack of data regarding autism prevalence and factors associated with it in Arab Countries, especially in Lebanon. A study conducted in Beirut and Mount Lebanon governorates estimated the prevalence of Autism Spectrum Disorder (ASD) at 1.53% of children 16-48 months attending nurseries. This study aims at obtaining a total national ASD estimate and find factors associated with the disorder. Methods: The methodology used to collect data at a national level consisted of administering the Modified Checklist for Autism in Toddlers (M-CHAT) for screening and a self-administered questionnaire for associated factors. The final sample included 1,373 children aged 16-48 months. Prevalence estimates and crude and adjusted Odds Ratios (ORs) with 95% confidence intervals (95% CI) were generated. Results: ASD national prevalence is 1.48% with 95% CI (0.84, 2.12), with a 1.13 male/female ratio according to the M-CHAT. In the multivariable analysis, having an employed mother in the last year was protective against ASD (OR (95% CI): 0.36(0.14, 0.93)). Presence of delivery complications was a risk factor (3.58 (1.26, 10.15)). First/ second born and moral support during pregnancy were protective, whereas mother not having a university education and family history of mental illness were risk factors. These variables were not significant in the multivariable analysis, probably due to small numbers. Conclusion: This is the first study estimating ASD prevalence in the entire Lebanese population, a much needed step to know the magnitude of the disorder. More robust studies are needed to better understand this disorder and factors associated with it in Lebanon and the region that have distinct cultural/environmental characteristics.
自闭症的国家患病率和相关因素:黎巴嫩横断面研究
背景:在阿拉伯国家,特别是黎巴嫩,缺乏关于自闭症患病率及其相关因素的数据。在贝鲁特省和黎巴嫩山省进行的一项研究估计,在参加托儿所的16-48个月儿童中,自闭症谱系障碍(ASD)的患病率为1.53%。本研究旨在获得全国ASD的总估计值,并找到与该障碍相关的因素。方法:在全国范围内收集数据的方法包括使用改良的幼儿自闭症检查表(M-CHAT)进行筛查,并使用自我管理的问卷调查相关因素。最后的样本包括1373名16-48个月大的儿童。得出了患病率估计值以及具有95%置信区间(95% CI)的粗比值比和校正比值比(ORs)。结果:根据M-CHAT,全国ASD患病率为1.48%,95% CI(0.84, 2.12),男女比例为1.13。在多变量分析中,去年有工作的母亲对ASD有保护作用(OR (95% CI): 0.36(0.14, 0.93))。存在分娩并发症是一个危险因素(3.58(1.26,10.15))。第一/第二胎和怀孕期间的精神支持具有保护作用,而母亲未受过大学教育和家族精神病史则是危险因素。这些变量在多变量分析中不显著,可能是由于数量少。结论:这是第一个估计整个黎巴嫩人口中ASD患病率的研究,是了解这种疾病严重程度的一个非常必要的步骤。需要进行更有力的研究,以便更好地了解黎巴嫩和该区域具有独特文化/环境特征的这种疾病及其相关因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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