Delta variant of SARS-CoV-2: characteristics and implications for public health in Colombia
Q3 Medicine
N. Yomayusa, R. Vega, A. Restrepo-Henao, L. Moron, C. Vaca, J. Oñate
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Abstract
The SARS-CoV-2 Delta variant has become one of the greatest public health challenges worldwide since, after being first identified in India in December 2020, it has spread rapidly, affecting mainly countries with low vaccination rates and those that have relaxed the public health and social measures implemented to control the COVID-19 pandemic. The Delta variant has a higher replication capacity and is associated with viral loads up to 1 260 times higher than those of infections caused by the original strain, which may be associated with an increased likelihood of hospitalization, ICU admission, need for oxygen therapy, pneumonia, or even death. Fully vaccinated individuals have almost similar protection against both Delta and Alpha variants. Given the impact of Delta in countries where it is the dominant variant, it is necessary for all countries to develop systematic action plans focused on implementing strict public health and social measures in the context of the COVID-19 pandemic and on increasing vaccination coverage. Bearing this in mind, the objective of this reflection paper is to describe the main characteristics of the Delta variant, its impact on the dynamics of the pandemic in some of the countries where it has been detected, the effectiveness of vaccines against this variant, and its implications for public health in Colombia. © 2021 Universidad Nacional de Colombia.
SARS-CoV-2的δ变体:特征及其对哥伦比亚公共卫生的影响
自2020年12月在印度首次发现SARS-CoV-2 Delta变体以来,它已成为全球最大的公共卫生挑战之一,并迅速传播,主要影响疫苗接种率低的国家以及为控制COVID-19大流行而放松公共卫生和社会措施的国家。Delta变体具有更高的复制能力,其病毒载量比原始菌株引起的感染高1260倍,这可能与住院、ICU住院、需要氧气治疗、肺炎甚至死亡的可能性增加有关。完全接种疫苗的个体对Delta和Alpha变体具有几乎相同的保护作用。鉴于德尔塔病毒在其占主导地位的国家产生的影响,所有国家都有必要制定系统的行动计划,重点是在2019冠状病毒病大流行背景下实施严格的公共卫生和社会措施,并提高疫苗接种覆盖率。考虑到这一点,本反思文件的目的是描述德尔塔病毒变体的主要特征、它对已发现这种变体的一些国家的大流行动态的影响、针对这种变体的疫苗的有效性以及它对哥伦比亚公共卫生的影响。©2021哥伦比亚国立大学
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