Multi-parametric imaging of atherosclerotic plaque by 50 MHz ultrasound and 3 Tesla magnetic resonance

S. Bridal, J. Toussaint, J. Raynaud, P. Fornés, A. Leroy-Willig, G. Berger
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引用次数: 2

Abstract

This study compares quantitative characterization of plaque by high resolution estimates of ultrasonic attenuation, ultrasonic backscatter and magnetic resonance transverse relaxation time. A total of 54 regions of in vitro human arteries were studied. Backscattered radio frequency signals were acquired with a 50 MHz backscatter acoustic microscope. Ultrasonic parametric images were constructed from the integrated (30 to 50 MHz) backscatter and attenuation obtained using FFT methods with diffraction correction and a multinarrow-band attenuation algorithm. Magnetic resonance images were constructed from estimates of the transverse relaxation time determined by an 8 echo-monoslice sequence at 3 Tesla. Histological segments obtained at each measurement site were used to identify tissue composition. Results suggest that combined ultrasound and magnetic resonance techniques may offer complementary information for plaque characterization.
动脉粥样硬化斑块的50 MHz超声和3特斯拉磁共振多参数成像
本研究通过超声衰减、超声后向散射和磁共振横向弛豫时间的高分辨率估计来比较斑块的定量表征。研究了54个离体人动脉区域。用50 MHz背向散射声显微镜采集射频信号。利用FFT方法对30 ~ 50 MHz的后向散射和衰减进行衍射校正和多箭头波段衰减算法,构建超声参数图像。磁共振图像是由3特斯拉的8回声单片序列确定的横向弛豫时间估计构建的。在每个测量点获得的组织学片段用于鉴定组织组成。结果表明,超声和磁共振联合技术可以为斑块表征提供补充信息。
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