Phytochemical Evaluation of Extracts and GC-MS analysis of oil from Monodora myristica Seed

W. Obonga, E. Omeje, C. Nnadi, Wilson G Ocheme
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引用次数: 3

Abstract

Monodora myristica is one of the plants used extensively in folkloric medicine across West Africa. Despite the ethnopharmacological relevance of the plant, the phytochemical details, especially of the oil-rich seed, have not been completely elucidated. This study was designed to ascertain the phytochemical constituents of extracts of M. myristica seed oil and characterize the oil constituent using gas chromatography-mass spectrometry. The phytochemical screening was done using standard methods and the oil was characterized by GC-MS analysis. The result of the phytochemical screening showed the presence of terpenoids, sterols, saponins, tannins, flavonoids and cardiac glycoside in variable quantities. The GC-MS analysis revealed huge presence of fatty acids, terpenoids and other related compounds. The major compounds found in the oil of the seeds were o-cymene (2), γ-terpinene (3), nopinane (4), limonene (5), carvotanacetone (6), β-pinene (7), aromadendrene (9), germacrene (11), α-amorphene (13) and copaene (14). The rich phytoconstituents present in the seed oil could be the basis of its acclaimed ethnomedicinal uses across West Africa and beyond. Dhaka Univ. J. Pharm. Sci. 18(1): 69-73, 2019 (June)
肉豆蔻种子提取物的植物化学评价及油的GC-MS分析
单念珠菌是西非民间医学中广泛使用的植物之一。尽管该植物具有民族药理学意义,但其植物化学细节,特别是富含油脂的种子,尚未完全阐明。本研究旨在确定肉豆蔻种子油提取物的植物化学成分,并采用气相色谱-质谱法对其进行表征。采用标准方法进行植物化学筛选,采用气相色谱-质谱分析对其进行表征。植物化学筛选结果显示,其中含有不同数量的萜类、甾醇类、皂苷类、单宁类、黄酮类和心糖苷。GC-MS分析显示大量脂肪酸、萜类化合物和其他相关化合物的存在。主要化合物有:o-伞花烯(2)、γ-松蒎烯(3)、诺蒎烯(4)、柠檬烯(5)、卡伏塔酮(6)、β-蒎烯(7)、芳香腺烯(9)、革烯(11)、α-阿莫菲烯(13)和copaene(14)。籽油中丰富的植物成分可能是西非及其他地区广受赞誉的民族医药用途的基础。达卡大学药学院。科学通报,18(1):69-73,2019 (6)
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