Diode-array UV spectrometric evidence for a concentration dependent phase transition in dilute aqueous solutions of pluronic F87 (poloxamer 237)

Abstract

Incubation of dilute polymer solutions with a KI–I2 standard shows the presence of a concentration dependent phase transition for the poly(oxyethylene)+ poly(oxypropylene)+ poly(oxyethylene) block copolymer F87 (P237) using diode-array UV spectrometry; the transition is shown to be reversible and reproducible and is in agreement with previous data obtained via high-sensitivity differential scanning microcalorimetry (HSDSC).