Gastroesophageal Reflux Disease and Hiatal Hernia

K. Perry, V. Wang
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引用次数: 5

Abstract

Gastroesophageal reflux disease (GERD) is common, affecting approximately 18 to 27% of adult Americans, and can have a considerable impact on quality of life. Hiatal hernias are present in 80% of patients with symptomatic GERD. This review covers the basic pathophysiology, evaluation, and treatment algorithms for patients with GERD and hiatal hernia. Figures show normal gastroesophageal junction anatomy, treatment algorithm for patients with symptomatic GERD, schematic and endoscopic images of long segment Barrett's esophagus, a normal barium esophagogram, esophageal intraluminal pressures assessed by esophageal manometry, test results from a 48-hour wireless pH study, laparoscopic Nissen fundoplication, laparoscopic gastroesophageal junction reinforcement, classification of paraesophageal hernia, and endoscopic view of Cameron ulcers at the level of the diaphragm in the setting of a type III paraesophageal hernia. Tables list risk factors for GERD and a standardized approach to Nissen fundoplication. This review contains 10 figures, 3 tables, and 68 references. Keywords: Gastroesophageal reflux disease, GERD, hiatal hernia, paraesophageal hernia, anti-reflux surgery, Nissen fundoplication, Barrett's esophagus, manometry, pH study
胃食管反流病和食管裂孔疝
胃食管反流病(GERD)很常见,约影响18%至27%的美国成年人,并对生活质量产生相当大的影响。80%的有症状的胃反流患者存在裂孔疝。本文综述了胃食管反流和裂孔疝的基本病理生理学、评估和治疗方法。图中显示正常胃食管交界处解剖、症状性胃食管反流患者的治疗方法、长段Barrett食管示意图及内镜图像、正常食管钡餐片、食管测压法评估的食管腔内压力、48小时无线pH值研究的测试结果、腹腔镜Nissen底翻术、腹腔镜胃食管交界处强化、食管旁疝分类、III型食道旁疝膈面Cameron溃疡的内窥镜观察。表列出了GERD的危险因素和尼森基金应用的标准化方法。本综述包含10个图,3个表,68篇参考文献。关键词:胃食管反流病,胃食管反流,食管裂孔疝,食管旁疝,抗反流手术,Nissen底复制,Barrett食管,测压,pH值研究
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